Genomics Core

The function of the Genomics Core is to provide access to skilled service and training in a suite of rapidly changing and expanding biological and computational technologies that enable the acquisition, manipulation, and interpretation of large amounts of data relating to gene location, sequence, sequence variation, expression and function these areas. The Genomics Core will provide centralized resources for the performance of molecular techniques relevant to a broad range of research efforts related to diabetes: DNA sequencing; SNP and microsatellite scoring ; Oligonucleotide and cDNA expression microarrays; Screening for sequence variants in DNA by denaturing high performance liquid chromatography (DHPLC); Screening pools of DNA for allele frequencies (pyrosequencing); and bioinformatics techniques and advice related to these methods.

The Core will also provide instruction/experience to students, fellows and faculty in the performance and interpretation of these techniques.